Peptide Database

Peptide NameSLAY-screened peptide P908

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC46H71N13O20

DescriptionStandard

        TYRNLDTDE
    

Molecular Weight1126.13 Da

Isoelectric Point (pI)4.32

Net Charge (pH 7.0)-2.59

Net Charge (pH 7.4) -2.79

Charge Density (pH 7.0) -0.2881

GRAVY Index-1.93

Hydrophobic Moment 0.32

Boman Index-0.51

Instability Index-12.89

Aliphatic Index 43.33

Aromaticity 0.1111

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 573.70

LogP -7.01

H-bond Donors 20.0

H-bond Acceptors 18.0

Rotatable Bonds 36.0

Heavy Atoms 79.0

Ring Count 1.0

Amide Bonds 9.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0002384 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/