Peptide Database

Peptide NameCyclic L27-11

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC87H143N27O16

DescriptionStandard

        TWLKKRRWKKAKPP
    

Molecular Weight1823.24 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)6.39

Net Charge (pH 7.4) 6.20

Charge Density (pH 7.0) 0.4567

GRAVY Index-2.04

Hydrophobic Moment 0.24

Boman Index-0.65

Instability Index114.79

Aliphatic Index 35.00

Aromaticity 0.1429

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 729.75

LogP -3.22

H-bond Donors 27.0

H-bond Acceptors 23.0

Rotatable Bonds 60.0

Heavy Atoms 130.0

Ring Count 6.0

Amide Bonds 13.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0225403 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyProtegrin

Tax ID32630

Structure & Mods

Confighead-to-tail cyclic peptide [Cyclic]

Chiralitynoncanonical stereochemical modification [Modified]

Bio-Activity Profile

Function

Antimicrobial

TargetEscherichia coli ATCC 259922

Activity64 μg/mL

MethodMIC

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