Peptide Database

Peptide NameC35

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antiviral

Antiviral ▸ Anti-HIV ▸ Anti-HIV-1

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition

Enzyme modulation ▸ Enzyme inhibition ▸ Integrase inhibition

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC169H262N48O52

DescriptionStandard

        LSELDDRADALQAGASQFETSAAKLKRKYWWKN
    

Molecular Weight3798.18 Da

Isoelectric Point (pI)8.38

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.55

Charge Density (pH 7.0) 0.0232

GRAVY Index-0.92

Hydrophobic Moment 0.50

Boman Index-0.21

Instability Index23.12

Aliphatic Index 65.45

Aromaticity 0.1212

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1670.90

LogP -16.55

H-bond Donors 59.0

H-bond Acceptors 53.0

Rotatable Bonds 129.0

Heavy Atoms 269.0

Ring Count 6.0

Amide Bonds 35.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0399443 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral

TargetHIV-1:Inhibition of 3′-end processing catalyzed by integrase

Activity200 μM

MethodIC50

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