Peptide Database

Peptide NameSnake venom vascular endothelial growth factor toxin vammin

Function Ontology

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length110 amino acids

Chemical FormulaC534H875N163O165S11

DescriptionStandard

        QVRPFLEVHERSACQARETLVPILQEYPDEISDIFRPSCVAVLRCSGCCTDESLKCTPVGKHTVDLQIMRVNPRTQSSKMEVMKFTEHTACECRPRRKQGEPDGPKEKPR
    

Molecular Weight12571.37 Da

Isoelectric Point (pI)8.19

Net Charge (pH 7.0)1.97

Net Charge (pH 7.4) 1.47

Charge Density (pH 7.0) 0.0179

GRAVY Index-0.69

Hydrophobic Moment 0.70

Boman Index-0.22

Instability Index68.18

Aliphatic Index 62.82

Aromaticity 0.0364

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5298.28

LogP -58.69

H-bond Donors 190.0

H-bond Acceptors 181.0

Rotatable Bonds 418.0

Heavy Atoms 873.0

Ring Count 17.0

Amide Bonds 116.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0333976 VERIFIED: YES

Provenance & Taxonomy

OrganismVipera ammodytes ammodytes [Animal]

FamilyPDGF/VEGF growth factor family

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermPyroglutamate

Disulfide14-56; 45-91; 49-93

Bio-Activity Profile

Function

Cytokine Growth factor PDGF VEGF growth factor family