Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length96 amino acids

Chemical FormulaC495H810N138O133S10

DescriptionStandard

        MKFLLLTLTVFLILFQMLPVCRGRKSCWIIKGHCRKDCKSGEQIKKPCRNGDYCCVPSKTVSQPQRPTQTTTRKYQTFTDKMKSNALLEQIPVIFQ
    

Molecular Weight11143.22 Da

Isoelectric Point (pI)9.79

Net Charge (pH 7.0)11.51

Net Charge (pH 7.4) 11.12

Charge Density (pH 7.0) 0.1199

GRAVY Index-0.31

Hydrophobic Moment 0.67

Boman Index-0.09

Instability Index35.59

Aliphatic Index 77.08

Aromaticity 0.0833

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4418.25

LogP -41.01

H-bond Donors 160.0

H-bond Acceptors 156.0

Rotatable Bonds 376.0

Heavy Atoms 776.0

Ring Count 16.0

Amide Bonds 105.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0181949 VERIFIED: NO

Provenance & Taxonomy

OrganismOvis aries [Animal]

FamilyDefensin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence