Peptide Database

Peptide NameColicin-D

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length711 amino acids

Chemical FormulaC3366H5296N910O1020S18

DescriptionStandard

        MDEYDFNGGVPPLPGNVWFPADEDGPGRWAAPTTGSQTGDILTVWPSNGYTPPDTSYLPPSTLGPGWADYDMAGVASDQGYLLYGVPVRVVLDILTEEGDWPGWTIGLYEAYREQEPVSAAMATLDRGLISGLPDPSRPAVVPYARLEPESPNPEKISRVMTIQPLNAVTDVPVNALPAPGGTVNVQRRLTDLVSGGNQYLVVTGGKPMSVRVVDASLVKDKTPQSDRFLKNTYQATIAPGLPPLIFTTDYINDSRMFPKNYVPNARGIISGQGVYGTAGYTSSTRNDDVIVRFPAGSGASPLYISSVEVLNPVSLHQRQLAETDIRNRIDAAIKTEENRKYLFGKAGIQETPAFTPEMVKSASALLTAPAAMMLNRAPAGIQLSATGTGVMTAVGEWAGSIAGALWRGAVGTAAASTAGPMVAAASTIFFSRPAGGGSDKVPGRDINMMAAQVSLFNTGKVKIEPGMKTVDLPVRGFISTDSNGRQSVMMVKTGSGGVPATVPVLSAVRDKATGLDKITVPAVAGAPSRTILINPVPVGPAAPSHTGNSTPVPVTPVHTGTDVKQAESIVTTTLPVADIPALQDFIYWQPDATGTGVEPIYVMLNSPPKSVTHKHKHYPPKGVSWKDIVNKTANGGSAKFKPDVNIPEIDVDAWENGQTTAKHPTWKVKKYDRVIGAYAGKETQWVVVKESQGVIHSHPVSEQKAKEYMK
    

Molecular Weight75408.71 Da

Isoelectric Point (pI)6.54

Net Charge (pH 7.0)-1.66

Net Charge (pH 7.4) -2.48

Charge Density (pH 7.0) -0.0023

GRAVY Index-0.20

Hydrophobic Moment 0.66

Boman Index0.09

Instability Index38.34

Aliphatic Index 79.80

Aromaticity 0.0703

Extinction Coeff. Reduced 105770.00

Extinction Coeff. Oxidized 105770.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0267273 VERIFIED: YES

Provenance & Taxonomy

OrganismEnterobacter wuhouensis [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)