Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length130 amino acids

Chemical FormulaC623H992N184O193S11

DescriptionStandard

        RGSSGANEYKYQHLFPQSTITKELTRVNERVKGSDHLKPLKPPEDEDVQLVAVAVALICICIQQSSATFAEIRELQELQEAVNNDGPAAEHQEVSADSWLMPYHRQKRGIKCRFCCGCCNSGVCGLCCRF
    

Molecular Weight14500.37 Da

Isoelectric Point (pI)6.46

Net Charge (pH 7.0)-0.96

Net Charge (pH 7.4) -1.55

Charge Density (pH 7.0) -0.0074

GRAVY Index-0.38

Hydrophobic Moment 0.71

Boman Index-0.07

Instability Index46.15

Aliphatic Index 75.77

Aromaticity 0.0615

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10595.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6096.07

LogP -67.56

H-bond Donors 217.0

H-bond Acceptors 207.0

Rotatable Bonds 484.0

Heavy Atoms 1011.0

Ring Count 19.0

Amide Bonds 143.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0403471 VERIFIED: NO

Provenance & Taxonomy

OrganismOreochromis niloticus [Animal]

FamilyHepcidin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal