Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length196 amino acids

Chemical FormulaC980H1561N273O265S8

DescriptionStandard

        PKTAPMAHEPMLLLAVTELVANSAAFTYFTAGALRRNFSSDTLPRQFPLQLRTKSMEVFSPELQERYPDQPMELHLWARQQPLLSCHPDALHGTLFSSAEAFVVLPNATRVPAFLLNIDANVTGKPTITRNRLGGTVRLTGLVPHPELAHISLPALCRAQGLPVPQVKRLETLLKFALWLFGVPRANSKCCSRPVP
    

Molecular Weight21664.07 Da

Isoelectric Point (pI)9.69

Net Charge (pH 7.0)7.46

Net Charge (pH 7.4) 7.01

Charge Density (pH 7.0) 0.0381

GRAVY Index0.00

Hydrophobic Moment 0.56

Boman Index0.07

Instability Index53.09

Aliphatic Index 95.10

Aromaticity 0.0714

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8451.87

LogP -104.86

H-bond Donors 292.0

H-bond Acceptors 286.0

Rotatable Bonds 684.0

Heavy Atoms 1526.0

Ring Count 43.0

Amide Bonds 210.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0393333 VERIFIED: NO

Provenance & Taxonomy

OrganismPycnonotus jocosus (Red-whiskered bulbul) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria