Peptide Database

Peptide NameFMRFamide-like

Function Ontology

Cardiovascular

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length17 amino acids

Chemical FormulaC90H122N22O32

DescriptionStandard

        SYGWAEGDTTDNEYLRF
    

Molecular Weight2024.06 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-3.53

Net Charge (pH 7.4) -3.75

Charge Density (pH 7.0) -0.2079

GRAVY Index-1.18

Hydrophobic Moment 0.40

Boman Index-0.10

Instability Index5.32

Aliphatic Index 28.82

Aromaticity 0.2353

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 900.05

LogP -9.08

H-bond Donors 32.0

H-bond Acceptors 29.0

Rotatable Bonds 62.0

Heavy Atoms 144.0

Ring Count 5.0

Amide Bonds 17.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0064560 VERIFIED: NO

Provenance & Taxonomy

OrganismCornu aspersum [Animal]

FamilyFMRFamide-like

Tax ID6535

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Cardiovascular

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0131599 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0201319 VERIFIED: NO

Provenance & Taxonomy

OrganismHelix aspersa [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide

RECORD: Rec_0411147 VERIFIED: NO

Provenance & Taxonomy

OrganismHelix aspersa [Animal]

FamilyFMRFamide related peptide

Tax ID6535

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

RFamide Neuropeptide Neuromodulator