Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length96 amino acids

Chemical FormulaC475H740N124O148S13

DescriptionStandard

        MNHSENYGLGVVMMCQCSFVLGKKCTLLVDDVDNGEEISNVGYSSFTIATCTLVDPDRCTKYFGYCRRHCFKYEKQIDICLSPSKICCIERLFEED
    

Molecular Weight10972.54 Da

Isoelectric Point (pI)5.06

Net Charge (pH 7.0)-4.40

Net Charge (pH 7.4) -4.90

Charge Density (pH 7.0) -0.0459

GRAVY Index-0.10

Hydrophobic Moment 0.57

Boman Index0.01

Instability Index40.36

Aliphatic Index 75.00

Aromaticity 0.1042

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 8075.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4395.97

LogP -43.00

H-bond Donors 162.0

H-bond Acceptors 159.0

Rotatable Bonds 366.0

Heavy Atoms 760.0

Ring Count 14.0

Amide Bonds 101.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0269747 VERIFIED: NO

Provenance & Taxonomy

OrganismNeomonachus schauinslandi [Animal]

FamilyDefensin

Tax ID29088

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence