Peptide Database

Peptide Namecycloviolacin O24

Function Ontology

Antiparasitic ▸ Anthelminthic

Antiparasitic ▸ Anthelminthic ▸ Nematicidal activity

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC119H175N33O40S5

DescriptionStandard

        GLPGETCFGGTCNTPGCTCDPWPVCTHN
    

Molecular Weight2868.18 Da

Isoelectric Point (pI)4.35

Net Charge (pH 7.0)-2.20

Net Charge (pH 7.4) -2.53

Charge Density (pH 7.0) -0.0785

GRAVY Index-0.24

Hydrophobic Moment 0.21

Boman Index0.17

Instability Index56.64

Aliphatic Index 24.29

Aromaticity 0.0714

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5750.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1120.26

LogP -16.05

H-bond Donors 41.0

H-bond Acceptors 44.0

Rotatable Bonds 79.0

Heavy Atoms 197.0

Ring Count 8.0

Amide Bonds 29.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0124755 VERIFIED: YES

Provenance & Taxonomy

OrganismViola odorata [Plant]

FamilyCyclotide

Tax ID97441

Structure & Mods

Confighead-to-tail cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Nematocidal Anthelmintic

TargetTrichostrongylus colubriformis

Activity2.99

MethodIC50

RECORD: Rec_0150829 VERIFIED: YES