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MYP_170472
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
11 amino acids
C56H81N13O16
Standard
Sequence
KGYGGVSLPEW
Physicochemical Analysis
1192.32 Da
6.00
-0.24
-0.45
-0.0217
-0.47
0.01
0.21
16.80
61.82
0.1818
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
465.10
-2.99
16.0
16.0
35.0
85.0
4.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0005687 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
0.8
IC50
PaperTavares T., del Mar Contreras M., Amorim M., Pintado M., Recio I., Malcata F. X.. Novel whey-derived peptides with inhibitory effect against angiotensin-converting enzyme: in vitro effect and stability to gastrointestinal enzymes. Peptides, 32, 1013-1019, 2011.
RECORD: Rec_0026496 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihypertensive
PaperAHTPDB: a comprehensive platform for analysis and presentation of antihypertensive peptides PMID25392419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25392419/
RECORD: Rec_0063348 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Glycomacropeptide
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Glycosylation-associated glycomacropeptide context
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme (ACE)
0.71 μM
IC50
PaperThe Portuguese Paradox: Why do some inhabitants of Portugal appear to live so long when their diet is based on whey cheese? | Tavares, TG. et al. | DOI: 10.1016/j.foodchem.2011.09.052 Evidence URLhttps://www.uniprot.org/uniprotkb/P00711/entry
RECORD: Rec_0096116 VERIFIED: NO
Provenance & Taxonomy
Salvia hispanica [Plant]
ACE-inhibitory peptide
4116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
Spontaneously hypertensive rat (SHR)
20 mmHg
SBP decrease
PaperWhey Proteins as Source of Bioactive Peptides Against Hypertension
RECORD: Rec_0118426 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
Angiotensin-converting enzyme
0.7 μM
IC50
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