Peptide Database

Peptide NameBeta-defensin 131A (Beta-defensin 31) (DEFB-31) (Defensin; beta 131)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC371H567N95O99S8

DescriptionStandard

        MRVLFFVFGVLSLMFTVPPARSFISNDECPSEYYHCRLKCNADEHAIRYCADFSICCKLKIIEIDGQKKW
    

Molecular Weight8198.57 Da

Isoelectric Point (pI)7.59

Net Charge (pH 7.0)0.62

Net Charge (pH 7.4) 0.20

Charge Density (pH 7.0) 0.0089

GRAVY Index0.12

Hydrophobic Moment 0.52

Boman Index0.07

Instability Index39.89

Aliphatic Index 83.57

Aromaticity 0.1429

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3105.44

LogP -21.70

H-bond Donors 114.0

H-bond Acceptors 110.0

Rotatable Bonds 267.0

Heavy Atoms 573.0

Ring Count 16.0

Amide Bonds 72.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0426002 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyBeta-defensin; Defensin

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic

TargetNo Target Organism Found