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MYP_170408
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Basic Information
Preptin
Cardiovascular
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Metabolic
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
34 amino acids
C187H275N47O53
Standard
Sequence
DVSTPPTVLPDNFPRYPVGKFFQYDTWKQSTQRL
Physicochemical Analysis
4029.47 Da
8.43
0.76
0.55
0.0223
-0.85
0.51
-0.10
33.49
48.53
0.1765
8480.00
8480.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1617.40
-14.64
54.0
54.0
120.0
287.0
12.0
37.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0014544 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Preptin
9606
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
4:O-linked (GalNAc...) threonine; 7:O-linked (GalNAc...) threonine
Bio-Activity Profile
Hormone Endocrine Cardiovascular Metabolic regulation Physiological regulation Growth regulation Development regulation Receptor modulation ACE inhibitory
a developmental stage and tissue
Mammalian: 1.1 hour; Yeast: 3 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Preptin (Homo sapiens): PMID 16912056 PMID16912056 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16912056/
RECORD: Rec_0201681 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 26.5%, E 5.9%, T 29.4%, C 38.2% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cell-Cell Communication
PaperNeuroPedia: neuropeptide database and spectral library PMID21821666 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21821666/
RECORD: Rec_0212288 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Preptin
9606
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
4:O-linked (GalNAc...) threonine; 7:O-linked (GalNAc...) threonine
Bio-Activity Profile
Hormone Endocrine Cardiovascular Metabolic regulation Physiological regulation Growth regulation Development regulation Receptor modulation ACE inhibitory
Mammalian: 1.1 hour; Yeast: 3 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Preptin (Homo sapiens): PMID 16912056 PMID16912056 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16912056/
RECORD: Rec_0377577 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
Insulin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone Metabolic
Evidence URLhttps://www.uniprot.org/uniprotkb/IGF2_HUMAN/entry