Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length57 amino acids

Chemical FormulaC242H408N70O80S7

DescriptionStandard

        MSTKDFNLDLVSVSKKDSGASPRITSISLCTPGCKTGALMGCAAATATCHCSIHVSK
    

Molecular Weight5802.70 Da

Isoelectric Point (pI)8.74

Net Charge (pH 7.0)2.62

Net Charge (pH 7.4) 2.22

Charge Density (pH 7.0) 0.0460

GRAVY Index0.19

Hydrophobic Moment 0.31

Boman Index0.09

Instability Index35.11

Aliphatic Index 73.68

Aromaticity 0.0175

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2383.14

LogP -33.75

H-bond Donors 90.0

H-bond Acceptors 92.0

Rotatable Bonds 192.0

Heavy Atoms 399.0

Ring Count 5.0

Amide Bonds 57.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0087123 VERIFIED: NO

Provenance & Taxonomy

OrganismLactococcus lactis [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

MethodQualitative functional evidence

RECORD: Rec_0255260 VERIFIED: NO