Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length423 amino acids

Chemical FormulaC2112H3293N531O625S15

DescriptionStandard

        MEKERFPDLTGHEKFGLGNVKYNISGIHVTAVELPSASISLLPGSGIKLVIGNASLTIDMNWNIRTWMFKDSGRSTVHISNVFVTAIFSTPRDNTSPTSISLTSCRTTSGDIDIKLNGKSGFLHNFFIKYLKKPIHRSLVTNSCPNIRAGIHLIDEDLQSLNVVMPIDDLAEVDYSLSSLPAVFQPFIDLDLKGTVFPAGNYTGSPYVVAPFTVTDQRDSMLFLAFSEYFFQTSSFAYYTAGAFNMTIAEETCSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPVISLEQDSFTVEIRGSMEVLAVLPDSTTQSLFTMNVAANSSISLNVFDQKLMGSLCLNRLQFSLAHSNVGFFEISLLDNILSYILQTEVIPSANAKLSKGFPLPNLANVTLTRPHITIAQGHILISTDVHYKH
    

Molecular Weight46603.90 Da

Isoelectric Point (pI)5.64

Net Charge (pH 7.0)-8.54

Net Charge (pH 7.4) -9.46

Charge Density (pH 7.0) -0.0202

GRAVY Index0.17

Hydrophobic Moment 0.77

Boman Index0.18

Instability Index43.20

Aliphatic Index 98.39

Aromaticity 0.0993

Extinction Coeff. Reduced 30370.00

Extinction Coeff. Oxidized 30620.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0004856 VERIFIED: NO

Provenance & Taxonomy

OrganismLepidothrix coronata [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria