Peptide Database

Peptide NameSLAY-screened peptide P5264

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC109H155N25O33S

DescriptionStandard

        PQSNYYLISMSDPNYWIGNI
    

Molecular Weight2375.61 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-1.04

Net Charge (pH 7.4) -1.11

Charge Density (pH 7.0) -0.0522

GRAVY Index-0.46

Hydrophobic Moment 0.33

Boman Index0.18

Instability Index81.78

Aliphatic Index 78.00

Aromaticity 0.2000

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 9970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 940.27

LogP -7.98

H-bond Donors 32.0

H-bond Acceptors 33.0

Rotatable Bonds 71.0

Heavy Atoms 168.0

Ring Count 7.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0188960 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/