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MYP_170323
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Basic Information
Bacteriocin TP
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
16 amino acids
C68H123N19O20
Standard
Sequence
ASVVNKLTGGVAGLLK
Physicochemical Analysis
1526.82 Da
10.00
1.79
1.60
0.1121
0.85
0.41
0.32
15.97
140.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
635.41
-6.78
22.0
22.0
52.0
107.0
0.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0140103 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25922
128 μM
MIC
PMID28254375 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28254375/
RECORD: Rec_0151356 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Human gastric cancer MKN 45
4.686 μM
IC50
PMID28254375 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28254375/
RECORD: Rec_0152340 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus CMCC 26003
10-20 μM
MIC
PMID28254375 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28254375/
RECORD: Rec_0154369 VERIFIED: YES
Provenance & Taxonomy
Bacillus spp [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
2.5 μM
MIC
RECORD: Rec_0191689 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
Bacteriocin
1423
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Mouse erythrocytes
<10 %
Hemolysis
PaperPubMed PMID: 28254375 PMID28254375 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28254375/
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