Peptide Database

Peptide NameDEFENSIN domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC430H707N137O143S7

DescriptionStandard

        MRTLAILAAILLFALLAQAKSLQETADDAATQEQPGEDDQDFAVSFEENGLSTLRASGSQARRTCRCRLGRCSRRESYSGSCNINGRIYSLCCR
    

Molecular Weight10308.50 Da

Isoelectric Point (pI)7.56

Net Charge (pH 7.0)0.46

Net Charge (pH 7.4) 0.14

Charge Density (pH 7.0) 0.0049

GRAVY Index-0.33

Hydrophobic Moment 0.67

Boman Index-0.13

Instability Index54.44

Aliphatic Index 78.09

Aromaticity 0.0532

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4609.77

LogP -60.04

H-bond Donors 171.0

H-bond Acceptors 151.0

Rotatable Bonds 351.0

Heavy Atoms 717.0

Ring Count 6.0

Amide Bonds 102.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0113017 VERIFIED: NO

Provenance & Taxonomy

OrganismPapio anubis [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence