Peptide Database

Peptide NameColicin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length830 amino acids

Chemical FormulaC4200H6536N1116O1262S16

DescriptionStandard

        MMRKKRGIDKISHIYYEKQDYLKFSEFEHDWGISHTPYGDIYHYDPGRFGGGRTGGDSFSDLPPISYSPDIYPYPGNSIDLGEITVNSGYPDTESTGEDPLYTDEPYLHTAHAGLAISMYPQQNTLKFILDMRNISAIVTPIKTYLLLALETVLPIAGRVLGIAGILMPSSIAEEPLVIYYHDNSYGDGDDDPYILTTLPATLVTGTSPEIFAGEKSVPADVIVSLAINEQEGKHTTVITPVKDKIIPVIKAEKTDIPSVYDVNIIPDAPPVRITVINNVKSIIVKPEQVSLTPPVKNYIPASPEIKTHHAIIDFSGEHEPVYLFLSQLPLFEEIESGNTIRLWQEQFPVEAARIAYQSAETELNNTTELRRKAISDRKNHREIDLESHMKKLAYYRRIASHSGYLERKYAKQIQQDIDRHFDVINQHKIAERNFMRAGIQKNRTERHLAMIVAGPEWLHRIRHFEKRLISLIENPDIFLIDGNKTGELQISVKGSGIIPQQNEEKPLFHDYLTNKKPDRNDSEDSIAGYHSAVIMQMNSIAGQMAVAVPAGNIRISDGFAERDCCGLWIRDKNTEKLVVIFDVHQYRRGKIPVINAVKDSITGVYKASLPSSATILINPVNPPIPPGFPGGISIPELKFPFHTGTSAEIPVTPMNTGFPLPDDISFTDFILVFPDGSGLKPVYIMLSSPYGETNAKGKFSGRDYHTERAGGPIEVLDWRIAVIDREGVDKVRLHISRFESSTDNDIMLERLEYILTGTFPATDTDKRFYTHEIRELERYRNLGIKDGVRPENEGEVWNNTHTATLEDYQLSSDKALLYTAEALFSTYDD
    

Molecular Weight93368.59 Da

Isoelectric Point (pI)5.43

Net Charge (pH 7.0)-27.02

Net Charge (pH 7.4) -28.89

Charge Density (pH 7.0) -0.0326

GRAVY Index-0.37

Hydrophobic Moment 0.70

Boman Index0.02

Instability Index39.57

Aliphatic Index 89.17

Aromaticity 0.0892

Extinction Coeff. Reduced 91110.00

Extinction Coeff. Oxidized 91235.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0328808 VERIFIED: YES

Provenance & Taxonomy

OrganismMorganella morganii SC01 [Bacterium]

FamilyPyocin/Colicin

Tax ID1239989

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic Non-ribosomal

TargetEscherichia coli