Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length367 amino acids

Chemical FormulaC1846H2901N499O527S7

DescriptionStandard

        AHQHGITILEKELAQLKLPDISGDSRVGRVGKVRYELSRLRLRDFHLPYSRITPISNVGLQVSISNAFAELDGDWRVKFLFVRDHGSFDLKVENVYIKISLRLGSDASGKPTVSTSDCSTRISNVRVLFSGKLGWLYNLFHSAIESRFRKILEDKVCDIVHESVQNELQTYVRTLPVTARIDARTGIDYSLVAPPRATAQSLDADLKGEFYSLAHRSPVPFSPLPLAFPSDHDRMVYFGASSYFFNTAGIAYHEAGALVFEITEDMIPKEAGFTLNTSVFSAFIPQLEQMYPNMPMKFRLSTPTAPFLTIGPGGISLKPIVEAQAYAILPDSSLAPLFLLSLVRNVSAVVNVRSGRLVGSLDVGRYR
    

Molecular Weight40741.26 Da

Isoelectric Point (pI)8.93

Net Charge (pH 7.0)4.60

Net Charge (pH 7.4) 3.85

Charge Density (pH 7.0) 0.0125

GRAVY Index0.00

Hydrophobic Moment 0.63

Boman Index0.07

Instability Index32.23

Aliphatic Index 98.01

Aromaticity 0.0981

Extinction Coeff. Reduced 30370.00

Extinction Coeff. Oxidized 30495.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0012849 VERIFIED: NO

Provenance & Taxonomy

OrganismMystacornis crossleyi [Plant]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria