MYP_170231
Potassium channel toxin alpha-KTx 18.1
Annotation / Sequence feature
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Nuclear export signal
Anticancer
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Cytotoxic anticancer activity
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Cytotoxic
Membrane / Ion-channel modulation
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Ion channel inhibition
Membrane / Ion-channel modulation
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Potassium channel modulation
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Potassium channel inhibitor
Toxicity / Safety
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Cytotoxicity
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Cytotoxic
Venom / Toxin
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General toxin
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Cytotoxic
Venom / Toxin
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General toxin
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Toxic
Venom / Toxin
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General toxin
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Toxin
Venom / Toxin
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Toxin
Standard
35 amino acids
C136H232N42O51S8
Standard
TGPQTTCQAAMCEAGCKGLGKSMESCQGDTCKCKA
3528.07 Da
7.47
0.34
0.05
0.0098
-0.42
0.48
-0.07
14.15
22.57
0.0000
0.00
375.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1510.56
-24.22
57.0
60.0
121.0
237.0
1.0
37.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0161705
VERIFIED: YES
Provenance & Taxonomy
Tityus obscurus [Animal]
Potassium channel inhibitor family
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
7-26; 12-31; 16-33
Bio-Activity Profile
Toxin
Venom
Potassium channel inhibitor family
Pathogenesis-associated
RECORD: Rec_0285195
VERIFIED: NO
Provenance & Taxonomy
Tityus cambridgei [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
7-26; 12-31; 16-33
Bio-Activity Profile
Toxin
Kv1
RECORD: Rec_0404641
VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Toxic
Cytotoxic