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MYP_170174
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Basic Information
Hedistin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
22 amino acids
C112H167N29O28
Standard
Sequence
LGAWLAGKVAGTVATYAWNRYV
Physicochemical Analysis
2367.70 Da
9.70
1.76
1.55
0.0799
0.47
0.36
0.32
12.66
97.73
0.1818
13980.00
13980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
917.93
-5.99
34.0
30.0
70.0
169.0
6.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0157533 VERIFIED: YES
Provenance & Taxonomy
Hediste diversicolor [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus (MRSA)
PaperPubMed PMID: 17210178 PMID17210178 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17210178/
RECORD: Rec_0179419 VERIFIED: YES
Provenance & Taxonomy
Hediste diversicolor [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Vibrio alginolyticus
PaperPubMed PMID: 17210178 PMID17210178 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17210178/
RECORD: Rec_0257872 VERIFIED: NO
Provenance & Taxonomy
Insecta [Animal]
50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0360385 VERIFIED: YES
Provenance & Taxonomy
Nereis diversicolor [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
such as V. alginolyticus
PaperHedistin: A novel antimicrobial peptide containing bromotryptophan constitutively expressed in the NK cells-like of the marine annelid, Nereis diversicolor
RECORD: Rec_0379075 VERIFIED: YES
Provenance & Taxonomy
Hediste diversicolor [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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