Peptide Database

Peptide NamePore-forming peptide ameobapore A (EH-APP; saposin-like protein)

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Standard StatusStandard

Sequence Length77 amino acids

Chemical FormulaC362H605N93O112S6

DescriptionStandard

        GEILCNLCTGLINTLENLLTTKGADKVKDYISSLCNKASGFIATLCTKVLDFGIDKLIQLIEDKVDANAICAKIHAC
    

Molecular Weight8244.62 Da

Isoelectric Point (pI)5.65

Net Charge (pH 7.0)-1.21

Net Charge (pH 7.4) -1.57

Charge Density (pH 7.0) -0.0157

GRAVY Index0.41

Hydrophobic Moment 0.68

Boman Index0.17

Instability Index24.71

Aliphatic Index 121.69

Aromaticity 0.0390

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3308.30

LogP -31.21

H-bond Donors 118.0

H-bond Acceptors 118.0

Rotatable Bonds 285.0

Heavy Atoms 573.0

Ring Count 4.0

Amide Bonds 82.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0377244 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anticancer

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