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MYP_170115
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Basic Information
Cycloviolacin VY1
Antimicrobial
Antiviral
Standard
31 amino acids
C138H226N34O42S6
Standard
Sequence
CGESCVFIPCITTVLGCSCSIKVCYKNGSIP
Physicochemical Analysis
3225.86 Da
7.77
0.70
0.40
0.0226
0.87
0.34
0.30
17.44
90.97
0.0645
1490.00
1865.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1192.78
-13.45
47.0
49.0
101.0
220.0
4.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0023077 VERIFIED: YES
Provenance & Taxonomy
Viola yedoensis [Plant]
Structure & Mods
backbone-cyclized peptide [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral
influenza A H1N1 virus
2.27 μM
IC50
RECORD: Rec_0112523 VERIFIED: YES
Provenance & Taxonomy
Viola yedoensis [Plant]
Cyclotide
Structure & Mods
head-to-tail cyclic cyclotide [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
influenza A virus H1N1
2.27 μg/mL
IC50
Paper[A cyclotide against influenza A H1N1 virus from Viola yedoensis]
RECORD: Rec_0133278 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0170251 VERIFIED: YES
Provenance & Taxonomy
Chassalia kolly [Plant]
Cyclotide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0296412 VERIFIED: YES
Provenance & Taxonomy
Insecta [Animal]
50557
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID21833535 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21833535/
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