Peptide Database

Peptide NameCaerin-1.6.1

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial

Enzyme modulation ▸ Enzyme inhibition ▸ nNOS inhibitor

Standard StatusStandard

Sequence Length22 amino acids

Chemical FormulaC110H180N28O26

DescriptionStandard

        FSVLGAVAKHVLPHVVPVIAEK
    

Molecular Weight2310.78 Da

Isoelectric Point (pI)8.61

Net Charge (pH 7.0)0.94

Net Charge (pH 7.4) 0.63

Charge Density (pH 7.0) 0.0425

GRAVY Index1.06

Hydrophobic Moment 0.43

Boman Index0.41

Instability Index31.95

Aliphatic Index 145.91

Aromaticity 0.0455

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 823.77

LogP -3.35

H-bond Donors 27.0

H-bond Acceptors 29.0

Rotatable Bonds 71.0

Heavy Atoms 164.0

Ring Count 5.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0000627 VERIFIED: YES

Provenance & Taxonomy

OrganismLitoria xanthomera [Animal]

FamilyCaerin

Structure & Mods

Configribosomal mature linear peptide [Linear]

ChiralityGene-encoded natural peptide composed of standard L-amino acids [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anticancer nNOS inhibitor

PaperP.A. Wabnitz et al. / European Journal of Biochemistry 267 (2000) 269-275. Differences in the skin peptides of the male and female Australian tree frog Litoria splendida. The discovery of the aquatic male sex pheromone splendipherin, together with phe8 caerulein and a new antibiotic peptide caerin 1.10 Evidence URLhttps://www.uniprot.org/uniprotkb/P62546/entry

RECORD: Rec_0042593 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0145948 VERIFIED: YES

Provenance & Taxonomy

OrganismLitoria chloris [Animal]

FamilyCaerin

Structure & Mods

Configribosomal mature linear peptide [Linear]

ChiralityGene-encoded natural peptide composed of standard L-amino acids [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anticancer nNOS inhibitor

PaperP.A. Wabnitz et al. / European Journal of Biochemistry 267 (2000) 269-275. Differences in the skin peptides of the male and female Australian tree frog Litoria splendida. The discovery of the aquatic male sex pheromone splendipherin, together with phe8 caerulein and a new antibiotic peptide caerin 1.10 Evidence URLhttps://www.uniprot.org/uniprotkb/P62547/entry