Peptide Database

Peptide NameNeurophysin 2

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length92 amino acids

Chemical FormulaC389H616N116O132S16

DescriptionStandard

        AMSDMELRQCLPCGPGGKGRCFGPSICCGEELGCFVGTAEALRCQEENYLPSPCQSGQKPCGSGGRCAAAGICCYEESCVTEPECREGAGIH
    

Molecular Weight9542.79 Da

Isoelectric Point (pI)4.72

Net Charge (pH 7.0)-5.23

Net Charge (pH 7.4) -5.70

Charge Density (pH 7.0) -0.0568

GRAVY Index-0.23

Hydrophobic Moment 0.48

Boman Index0.02

Instability Index58.63

Aliphatic Index 47.83

Aromaticity 0.0435

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3905.46

LogP -51.56

H-bond Donors 145.0

H-bond Acceptors 144.0

Rotatable Bonds 309.0

Heavy Atoms 653.0

Ring Count 12.0

Amide Bonds 96.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0118859 VERIFIED: YES

Provenance & Taxonomy

OrganismLoxodonta africana [Animal]

FamilyVasopressin/oxytocin

Tax ID9785

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide10-13

Bio-Activity Profile

Function

Neurohypophyseal hormone Neuropeptide

RECORD: Rec_0194174 VERIFIED: YES

Provenance & Taxonomy

OrganismLoxodonta africana [Animal]

FamilyNeurophysin

Tax ID9785

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide10-54; 13-27; 21-44; 28-34; 61-73; 67-85; 74-79

Bio-Activity Profile

Function

Hormone Endocrine

Half-LifeMammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour