Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC362H599N101O98S9

DescriptionStandard

        MKFLLILTVALLLAQLTPAMKCWSALGRCRTTCQESEVFHILCRDATMCCVHPKYIPIKPESSNRAGRLGTSVV
    

Molecular Weight8222.83 Da

Isoelectric Point (pI)9.12

Net Charge (pH 7.0)4.62

Net Charge (pH 7.4) 4.20

Charge Density (pH 7.0) 0.0624

GRAVY Index0.37

Hydrophobic Moment 0.67

Boman Index0.11

Instability Index36.04

Aliphatic Index 101.49

Aromaticity 0.0541

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3160.42

LogP -27.77

H-bond Donors 118.0

H-bond Acceptors 114.0

Rotatable Bonds 269.0

Heavy Atoms 570.0

Ring Count 11.0

Amide Bonds 76.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0341418 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyDefensin

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence