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MYP_169926
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Basic Information
HEXIM1 (147-164)[K4,5,6,13,14,15R], BR-RRR12
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
18 amino acids
C104H180N54O21
Standard
Sequence
QLGRRRHRRRPSRRRRHW
Physicochemical Analysis
2522.89 Da
12.00
9.93
9.63
0.5519
-3.04
0.45
-1.37
284.10
21.67
0.0556
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1304.70
-15.63
53.0
33.0
86.0
179.0
5.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0145368 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Human breast adenocarcinoma MDA-MB-231[20-30% Killing = 100 microM]
PMID26734838 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26734838/
RECORD: Rec_0163265 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
μM
100 μM
Cytotoxicity
PaperPubMed PMID: 26734838 PMID26734838 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26734838/
RECORD: Rec_0184985 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Enterococcus faecalis
32 μM
MIC
PMID26734838 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26734838/
RECORD: Rec_0189992 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Enterococcus faecalis VR
16 μM
MIC
PMID26734838 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26734838/
RECORD: Rec_0247099 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25922
64 μM
MBC
PMID26734838 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26734838/
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