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MYP_169922
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Basic Information
MCCL28
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
114 amino acids
C540H909N195O162S8
Standard
Sequence
FQTSEAILPMASSCCTEVSHHVSGRLLERVSSCSIQRADGDCDLAAVILHVKRRRICISPHNRTLKQWMRASEVKKNGRENVCSGKKQPSRKDRKGHTTRKHRTRGTHRHEASR
Physicochemical Analysis
12981.72 Da
10.67
15.41
14.69
0.1352
-0.94
0.77
-0.35
59.35
61.58
0.0175
5500.00
5875.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
5874.29
-76.78
221.0
193.0
449.0
905.0
14.0
120.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0058323 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
10090
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa
1.7± 0.1 μM
IC50
PMID12538707 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12538707/
RECORD: Rec_0085772 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans, Pseudomonas aeruginosa, Klebsiella pneumoniae, S. mutans, S. pyogenes, and Staphylococcus aureus
0.9-4.5 μM
IC50
PaperCCL28 has dual roles in mucosal immunity as a chemokine with broad-spectrum antimicrobial activity
RECORD: Rec_0087241 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]; Mammalia [Animal]
10090; 40674
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID12538707 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12538707/
RECORD: Rec_0178373 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
10090
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Streptococcus mutans
1.5± 0.3 μM
IC50
PMID12538707 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12538707/
RECORD: Rec_0191328 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
10090
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Streptococcus pyogenes
4.5± 0.4 μM
IC50
PMID12538707 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12538707/
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