Peptide Database

Peptide NameRelaxin B chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC138H234N42O40S2

DescriptionStandard

        QKPDDVIKACGRELARLRIEICGSLSWK
    

Molecular Weight3185.72 Da

Isoelectric Point (pI)8.86

Net Charge (pH 7.0)1.75

Net Charge (pH 7.4) 1.50

Charge Density (pH 7.0) 0.0623

GRAVY Index-0.35

Hydrophobic Moment 0.77

Boman Index-0.16

Instability Index46.37

Aliphatic Index 101.07

Aromaticity 0.0357

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1352.53

LogP -12.08

H-bond Donors 50.0

H-bond Acceptors 44.0

Rotatable Bonds 110.0

Heavy Atoms 222.0

Ring Count 3.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0013303 VERIFIED: YES

Provenance & Taxonomy

OrganismEquus caballus [Animal]

FamilyRelaxin

Tax ID9796

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Bio-Activity Profile

Function

Hormone Endocrine

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour

RECORD: Rec_0137413 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0340354 VERIFIED: YES

Provenance & Taxonomy

OrganismEquus caballus [Animal]

FamilyInsulin

Tax ID9796

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermPyroglutamate

Bio-Activity Profile

Function

Hormone Metabolic