Peptide Database

Peptide NameCycloviolacin VY1

Function Ontology

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Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC120H196N32O37S6

DescriptionStandard

        CGESCVFIPCISSVVGCSCKNKVCYKN
    

Molecular Weight2871.42 Da

Isoelectric Point (pI)8.33

Net Charge (pH 7.0)1.70

Net Charge (pH 7.4) 1.40

Charge Density (pH 7.0) 0.0629

GRAVY Index0.54

Hydrophobic Moment 0.35

Boman Index0.14

Instability Index41.08

Aliphatic Index 71.85

Aromaticity 0.0741

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1113.82

LogP -13.77

H-bond Donors 44.0

H-bond Acceptors 45.0

Rotatable Bonds 93.0

Heavy Atoms 195.0

Ring Count 3.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0368838 VERIFIED: YES

Provenance & Taxonomy

OrganismMelicytus ramiflorus [Plant]

FamilyCyclotide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)