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MYP_169864
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Basic Information
Brevinin-2MP
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antifungal
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
30 amino acids
C135H238N40O41S2
Standard
Sequence
GVITDTLKGVAKTVAAELLRKAHCKLTNSC
Physicochemical Analysis
3141.71 Da
9.31
2.83
2.54
0.0942
0.21
0.59
0.04
5.61
107.33
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1320.72
-14.67
49.0
47.0
108.0
218.0
1.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0081019 VERIFIED: YES
Provenance & Taxonomy
Microhyla pulchra [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
24-30
Bio-Activity Profile
Antimicrobial Antifungal Anti-inflammatory
Escherichia coli ATCC 25922
47.78 μM
MIC
PaperAntimicrobial and Anti-inflammatory Effects of a Novel Peptide From the Skin of Frog Microhyla pulchra.
RECORD: Rec_0132941 VERIFIED: YES
Provenance & Taxonomy
Microhyla pulchra [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
24-30
Bio-Activity Profile
Antimicrobial Antifungal Anti-inflammatory
Staphylococcus aureus ATCC 25923
47.78 μM
MIC
PaperAntimicrobial and Anti-inflammatory Effects of a Novel Peptide From the Skin of Frog Microhyla pulchra.
RECORD: Rec_0164520 VERIFIED: YES
Provenance & Taxonomy
Animalia [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID34975482 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34975482/
RECORD: Rec_0207244 VERIFIED: YES
Provenance & Taxonomy
Microhyla pulchra [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
24-30
Bio-Activity Profile
Antimicrobial Antifungal Anti-inflammatory
Pseudomonas aeruginosa ATCC 27853
>100 μM
MIC
PaperAntimicrobial and Anti-inflammatory Effects of a Novel Peptide From the Skin of Frog Microhyla pulchra.
RECORD: Rec_0284817 VERIFIED: YES
Provenance & Taxonomy
Microhyla pulchra [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
24-30
Bio-Activity Profile
Antimicrobial Antifungal Anti-inflammatory
fungi Candida albicans ATCC 10231
59.73 μM
MIC
PaperAntimicrobial and Anti-inflammatory Effects of a Novel Peptide From the Skin of Frog Microhyla pulchra.
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