Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length190 amino acids

Chemical FormulaC961H1515N263O261S8

DescriptionStandard

        PKTPPMAHEPMLLLAVTEFVANSAAFTYFTAGALRRNFSSDMLPRQFPLQLRTKNMEVFSPELQERYPDQPMELHLWARQQPLLSCHPDALHGTLFTSAEAFVVLPNATRVPAFLLNIDANVTGKPTITRNRLGGTVRLTGSVPDPQLAWTALPELCRAQGLPVPQVKRLETLLKFALWLFGVPRANSKC
    

Molecular Weight21185.44 Da

Isoelectric Point (pI)9.46

Net Charge (pH 7.0)5.30

Net Charge (pH 7.4) 4.97

Charge Density (pH 7.0) 0.0279

GRAVY Index-0.07

Hydrophobic Moment 0.56

Boman Index0.07

Instability Index47.27

Aliphatic Index 89.89

Aromaticity 0.0842

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19605.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8265.61

LogP -96.80

H-bond Donors 283.0

H-bond Acceptors 278.0

Rotatable Bonds 669.0

Heavy Atoms 1493.0

Ring Count 43.0

Amide Bonds 206.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0015433 VERIFIED: NO

Provenance & Taxonomy

OrganismDonacobius atricapilla [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria