Peptide Database

Peptide NameGranulocyte colony-stimulating factor

Function Ontology

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length174 amino acids

Chemical FormulaC843H1353N233O245S8

DescriptionStandard

        TPLGPARSLPQSFLLKCLEQVRKIQADGAELQERLCAAHKLCHPEELMLLRHSLGIPQAPLSSCSSQSLQLTSCLNQLHGGLFLYQGLLQALAGISPELAPTLDTLQLDVTDFATNIWLQMEDLGAAPAVQPTQGAMPTFTSAFQRRAGGVLVASQLHRFLELAYRGLRYLAEP
    

Molecular Weight18928.69 Da

Isoelectric Point (pI)6.16

Net Charge (pH 7.0)-2.19

Net Charge (pH 7.4) -2.73

Charge Density (pH 7.0) -0.0126

GRAVY Index0.07

Hydrophobic Moment 0.89

Boman Index0.11

Instability Index64.15

Aliphatic Index 104.43

Aromaticity 0.0575

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10220.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7569.83

LogP -80.29

H-bond Donors 260.0

H-bond Acceptors 256.0

Rotatable Bonds 618.0

Heavy Atoms 1329.0

Ring Count 28.0

Amide Bonds 191.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0251151 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyIL-6 superfamily

Tax ID9913; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide36-42; 64-74

Bio-Activity Profile

Function

Cytokine Growth factor IL-6 superfamily