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MYP_169816
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Basic Information
Saha-CATH6
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
29 amino acids
C168H278N60O41
Standard
Sequence
KRIRFFERIRDRLRDLGNRIKNRIRDFFS
Physicochemical Analysis
3794.38 Da
11.91
6.76
6.55
0.2332
-1.16
0.84
-0.62
16.48
80.69
0.1379
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1742.87
-15.49
66.0
48.0
135.0
269.0
4.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0327029 VERIFIED: YES
Provenance & Taxonomy
Sarcophilus harrisii [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
S. anginosus
64 μg/mL
MIC
PMID27725697 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27725697/
RECORD: Rec_0335454 VERIFIED: YES
Provenance & Taxonomy
Sarcophilus harrisii [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida glabrata
64 μg/mL
MIC
PMID27725697 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27725697/
RECORD: Rec_0366129 VERIFIED: YES
Provenance & Taxonomy
Sarcophilus harrisii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer Cytotoxic
DFT1 1426 cells
Cell viability assay
PaperTasmanian devil cathelicidins exhibit anticancer activity against Devil Facial Tumour Disease (DFTD) cells PMID37542170 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/37542170/
RECORD: Rec_0375038 VERIFIED: YES
Provenance & Taxonomy
Sarcophilus harrisii [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Enterococcus faecalis
64 μg/mL
MIC
PMID27725697 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27725697/
RECORD: Rec_0377079 VERIFIED: YES
Provenance & Taxonomy
Sarcophilus harrisii [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Cryptococcus neoformans
64 μg/mL
MIC
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