Peptide Database

Peptide NameHNP-1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length75 amino acids

Chemical FormulaC360H563N103O105S7

DescriptionStandard

        EPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGSRKNMACYCRIPACIAGERRYGTCIYQGRLWAFCC
    

Molecular Weight8238.40 Da

Isoelectric Point (pI)5.72

Net Charge (pH 7.0)-1.12

Net Charge (pH 7.4) -1.45

Charge Density (pH 7.0) -0.0150

GRAVY Index-0.08

Hydrophobic Moment 0.49

Boman Index0.03

Instability Index51.29

Aliphatic Index 79.60

Aromaticity 0.0800

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3297.35

LogP -30.55

H-bond Donors 119.0

H-bond Acceptors 112.0

Rotatable Bonds 259.0

Heavy Atoms 575.0

Ring Count 15.0

Amide Bonds 78.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0111843 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDefensin

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive

TargetStaphylococcus aureus