Peptide Database

Peptide NameCecropin A

Function Ontology

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Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC189H313N53O46S

DescriptionStandard

        RWKIFKKIEKMGWNIRDGIVKAGPAIEVLGSAKAVGK
    

Molecular Weight4095.90 Da

Isoelectric Point (pI)10.38

Net Charge (pH 7.0)5.76

Net Charge (pH 7.4) 5.54

Charge Density (pH 7.0) 0.1557

GRAVY Index-0.15

Hydrophobic Moment 0.73

Boman Index0.02

Instability Index62.92

Aliphatic Index 97.57

Aromaticity 0.0811

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1614.87

LogP -10.22

H-bond Donors 57.0

H-bond Acceptors 53.0

Rotatable Bonds 143.0

Heavy Atoms 289.0

Ring Count 6.0

Amide Bonds 37.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0085039 VERIFIED: YES

Provenance & Taxonomy

OrganismBombyx mori [Animal]

FamilyCecropin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)