Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length56 amino acids

Chemical FormulaC254H422N68O84S9

DescriptionStandard

        MAKFDDFDLDIVVKKQDNTVQPNVTSKSLCTPGCITGVLMCLTQNSCVSCNSCIKC
    

Molecular Weight6061.06 Da

Isoelectric Point (pI)5.88

Net Charge (pH 7.0)-0.57

Net Charge (pH 7.4) -0.90

Charge Density (pH 7.0) -0.0101

GRAVY Index0.17

Hydrophobic Moment 0.41

Boman Index0.06

Instability Index42.12

Aliphatic Index 81.61

Aromaticity 0.0357

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2466.77

LogP -30.70

H-bond Donors 89.0

H-bond Acceptors 93.0

Rotatable Bonds 203.0

Heavy Atoms 415.0

Ring Count 4.0

Amide Bonds 62.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0083588 VERIFIED: NO

Provenance & Taxonomy

OrganismAneurinibacillus thermoaerophilus [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

MethodQualitative functional evidence