Peptide Database

Peptide NameInsulin B chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC144H212N38O40S3

DescriptionStandard

        MAPPQHLCGSHLVDALYLVCGDRGFFYNS
    

Molecular Weight3211.65 Da

Isoelectric Point (pI)5.94

Net Charge (pH 7.0)-1.34

Net Charge (pH 7.4) -1.70

Charge Density (pH 7.0) -0.0464

GRAVY Index0.21

Hydrophobic Moment 0.34

Boman Index0.22

Instability Index34.37

Aliphatic Index 80.69

Aromaticity 0.1379

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1221.50

LogP -10.32

H-bond Donors 43.0

H-bond Acceptors 44.0

Rotatable Bonds 97.0

Heavy Atoms 225.0

Ring Count 8.0

Amide Bonds 30.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0404377 VERIFIED: YES

Provenance & Taxonomy

OrganismBatrachoididae [Animal]

FamilyInsulin

Tax ID8065

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour