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MYP_169609
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Basic Information
RJ2-W9,16
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Enzyme modulation ▸ Enzyme inhibition ▸ Infection inhibition
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
21 amino acids
C106H180N32O22
Standard
Sequence
KAAKKAAKWAKKAAKWAKKAA
Physicochemical Analysis
2254.76 Da
10.90
8.75
8.53
0.4167
-0.90
0.72
-0.27
-4.79
47.62
0.0952
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
911.08
-6.10
33.0
31.0
81.0
160.0
4.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0082477 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-HSV Entry inhibition
Herpes simplex virus 1(HSV-1) | Vero cells
111 μM
IC50
Mammalian: 1.3 h; Yeast: 3 min; E. coli: 2 min
PaperPrediction of activity, synthesis and biological testing of anti-HSV active peptides. | Jenssen H, Gutteberg TJ, Rekdal Ø, Lejon T. | Chem Biol Drug Des. 2006 Jul;68(1):58-66. | DOI:10.1111/j.1747-0285.2006.00412.x | PMID:16923027 PMID16923027 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16923027/
RECORD: Rec_0145755 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-HSV Infection inhibition
Herpes simplex virus 2(HSV-2) | MRC-5 cells
48 μM
IC50
Mammalian: 1.3 h; Yeast: 3 min; E. coli: 2 min
PaperPrediction of activity, synthesis and biological testing of anti-HSV active peptides. | Jenssen H, Gutteberg TJ, Rekdal Ø, Lejon T. | Chem Biol Drug Des. 2006 Jul;68(1):58-66. | DOI:10.1111/j.1747-0285.2006.00412.x | PMID:16923027 PMID16923027 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16923027/
RECORD: Rec_0156030 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Infection inhibition
Inhibition of viral infection in MRC-5 cells
32 μM
IC50
Mammalian: 1.3 h; Yeast: 3 min; E. coli: 2 min
PaperPrediction of activity, synthesis and biological testing of anti-HSV active peptides. | Jenssen H, Gutteberg TJ, Rekdal Ø, Lejon T. | Chem Biol Drug Des. 2006 Jul;68(1):58-66. | DOI:10.1111/j.1747-0285.2006.00412.x | PMID:16923027 PMID16923027 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16923027/
RECORD: Rec_0219396 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
PaperPubMed PMID: 16923027 PMID16923027 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16923027/
RECORD: Rec_0238554 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
Herpes simplex virus 1(HSV-1):inhibition of viral entry into Vero cells
111 μM
IC50
PaperPubMed PMID: 16923027 PMID16923027 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16923027/
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