Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC471H742N128O137S8

DescriptionStandard

        MRFLLLVLPVLALLPQVTPDYGAKKRCLKILGHCRRHCKDGEMDHGSCKYYRVCCVPDLNSYNQNYAITWTTEETSTSEYDLSSDFIGVLRAI
    

Molecular Weight10646.23 Da

Isoelectric Point (pI)7.60

Net Charge (pH 7.0)0.71

Net Charge (pH 7.4) 0.23

Charge Density (pH 7.0) 0.0076

GRAVY Index-0.15

Hydrophobic Moment 0.60

Boman Index0.00

Instability Index40.62

Aliphatic Index 90.11

Aromaticity 0.0968

Extinction Coeff. Reduced 14440.00

Extinction Coeff. Oxidized 14815.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4261.28

LogP -38.26

H-bond Donors 156.0

H-bond Acceptors 149.0

Rotatable Bonds 347.0

Heavy Atoms 744.0

Ring Count 17.0

Amide Bonds 97.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0087216 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyDefensin

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence