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MYP_169502
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Basic Information
LL-37(1-4;17-27)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
15 amino acids
C86H142N24O21
Standard
Sequence
LLGDFKRIVQRIKDF
Physicochemical Analysis
1848.20 Da
9.99
1.76
1.55
0.1174
-0.09
0.89
-0.13
-0.33
123.33
0.1333
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
764.25
-3.86
27.0
23.0
65.0
131.0
2.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0013009 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PMID16637646 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16637646/
RECORD: Rec_0031403 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
LL-37/Cathelicidin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial
KBv
MTT/MTS assay
PMID16637646 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16637646/
RECORD: Rec_0059293 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Cathelicidin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli K12
250 μM
MIC
PMID16637646 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16637646/
RECORD: Rec_0084246 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 40.0%, E 0.0%, T 33.3%, C 26.7% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Antibacterial Antimicrobial
PaperCancerPPD: a database of anticancer peptides and proteins PMID25270878 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25270878/
RECORD: Rec_0139813 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Evidence URLhttps://patents.google.com/patent/US20080125359A1/en PatentUS 2008/0125359 A1
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