Peptide Database

Peptide NameSLAY-screened peptide P340

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC57H102N18O17S

DescriptionStandard

        NKCRPISKADVL
    

Molecular Weight1343.60 Da

Isoelectric Point (pI)9.31

Net Charge (pH 7.0)1.75

Net Charge (pH 7.4) 1.53

Charge Density (pH 7.0) 0.1458

GRAVY Index-0.41

Hydrophobic Moment 0.33

Boman Index-0.24

Instability Index37.88

Aliphatic Index 97.50

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 589.19

LogP -6.20

H-bond Donors 21.0

H-bond Acceptors 20.0

Rotatable Bonds 45.0

Heavy Atoms 93.0

Ring Count 1.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0380902 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/