Peptide Database

Peptide NameCyclotide Viphi D

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC130H211N35O41S6

DescriptionStandard

        CGESCVFIPCISSVIGCSCSSKVCYRNGIP
    

Molecular Weight3112.67 Da

Isoelectric Point (pI)7.77

Net Charge (pH 7.0)0.70

Net Charge (pH 7.4) 0.41

Charge Density (pH 7.0) 0.0234

GRAVY Index0.75

Hydrophobic Moment 0.37

Boman Index0.23

Instability Index29.01

Aliphatic Index 81.00

Aromaticity 0.0667

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1199.56

LogP -15.63

H-bond Donors 48.0

H-bond Acceptors 48.0

Rotatable Bonds 97.0

Heavy Atoms 212.0

Ring Count 4.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0105455 VERIFIED: YES

Provenance & Taxonomy

OrganismViola philippica [Plant]

FamilyCyclotide

Tax ID39648

Structure & Mods

Confighead-to-tail cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidemultiple disulfide bonds reported, sites not specified

Bio-Activity Profile

Function

Cytotoxic

RECORD: Rec_0426074 VERIFIED: NO