Peptide Database

Peptide NameIpilimumab

Function Ontology

Anticancer

Immunology ▸ Immunomodulation ▸ Immunogen

Immunology ▸ Immunomodulation ▸ Immuno-oncology

Standard StatusStandard

Sequence Length448 amino acids

Chemical FormulaC2200H3399N587O669S15

DescriptionStandard

        QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYTMHWVRQAPGKGLEWVTFISYDGNNKYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAIYYCARTGWLGPFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
    

Molecular Weight49256.03 Da

Isoelectric Point (pI)8.70

Net Charge (pH 7.0)7.55

Net Charge (pH 7.4) 6.56

Charge Density (pH 7.0) 0.0168

GRAVY Index-0.40

Hydrophobic Moment 0.48

Boman Index0.01

Instability Index47.34

Aliphatic Index 70.38

Aromaticity 0.0982

Extinction Coeff. Reduced 79300.00

Extinction Coeff. Oxidized 79925.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0300826 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyMonoclonal antibody

Tax ID9606

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anticancer Immuno-oncology Vaccine Immunogen

Half-Life14.7 days