MYP_169394
SL-ENF(Sialic acid Enfuvirtide)
Antiviral
▸
Antiviral mechanism
▸
Viral fusion inhibition
▸
Standard
37 amino acids
C205H303N51O65S
Standard
CYTSLIHSLIEESQNQQEKNEQELLELDKWASLWNWF
4553.97 Da
4.30
-5.15
-5.43
-0.1391
-0.78
0.46
-0.04
61.23
87.03
0.1351
17990.00
17990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1923.12
-15.54
65.0
62.0
153.0
322.0
9.0
43.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0234386
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Sialic acid
Amidation
Bio-Activity Profile
Anti-viral potency
0.002 μM
EC50
Sprague-Dawey (SD) rats Plasma, in vivo; 83160 s
RECORD: Rec_0264339
VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
None
Mal-PEG12-CP was conjugated to Cys-enfuvirtide
Bio-Activity Profile
Antiretroviral fusion inhibitor
0.051 μM
LC-MS/MS
Female Wistar rats, in vivo; 37440 s
RECORD: Rec_0273303
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Lactic acid
Amidation
Bio-Activity Profile
Anti-viral potency
0.002 μM
EC50
Sprague-Dawey (SD) rats Plasma, in vivo; 15120 s