Peptide Database

Peptide NameInsulin-2 B chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC151H224N40O40S2

DescriptionStandard

        AAPPQHLCGSHLVDALYLVCGERGFFYNPK
    

Molecular Weight3303.77 Da

Isoelectric Point (pI)6.94

Net Charge (pH 7.0)-0.05

Net Charge (pH 7.4) -0.37

Charge Density (pH 7.0) -0.0016

GRAVY Index0.05

Hydrophobic Moment 0.36

Boman Index0.18

Instability Index28.48

Aliphatic Index 81.33

Aromaticity 0.1333

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1247.60

LogP -9.54

H-bond Donors 43.0

H-bond Acceptors 44.0

Rotatable Bonds 99.0

Heavy Atoms 233.0

Ring Count 9.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0157014 VERIFIED: NO

Provenance & Taxonomy

OrganismKatsuwonus pelamis [Animal]

FamilyInsulin

Tax ID8226

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour