‹ ›
MYP_169357
← PREVIOUS NEXT → BACK
Basic Information
HPIV3 F HRC derived peptide(457-484)
Antimicrobial
Antiviral
Antiviral ▸ Anti-Influenza virus
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor
Standard
28 amino acids
C142H238N42O49
Standard
Sequence
SIELNKAKSDLEESKEWIRRSNQKLDSI
Physicochemical Analysis
3317.66 Da
6.06
-0.53
-0.75
-0.0189
-1.23
0.66
-0.37
84.25
87.14
0.0357
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1546.91
-17.06
54.0
49.0
121.0
233.0
2.0
30.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0178866 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
Henda virus(HeV):inhibition of virus infection in HeLa cells
10 μM
IC50
PaperPubMed PMID: 16973588 PMID16973588 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16973588/
RECORD: Rec_0238056 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0267823 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Fusion inhibition
inhibition of fusion in HeLa cells
1 μM
IC50
Mammalian: 1.9 h; Yeast: >20 h; E. coli: >10 h
PaperInhibition of hendra virus fusion. | Porotto M, Doctor L, Carta P, Fornabaio M, Greengard O, Kellogg GE, Moscona A. | J Virol. 2006 Oct;80(19):9837-49. | DOI:10.1128/JVI.00736-06 | PMID:16973588 PMID16973588 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16973588/
RECORD: Rec_0308257 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Fusion inhibition
inhibition of fusion in HeLa cells
10 μM
IC50
Mammalian: 1.9 h; Yeast: >20 h; E. coli: >10 h
PaperInhibition of hendra virus fusion. | Porotto M, Doctor L, Carta P, Fornabaio M, Greengard O, Kellogg GE, Moscona A. | J Virol. 2006 Oct;80(19):9837-49. | DOI:10.1128/JVI.00736-06 | PMID:16973588 PMID16973588 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16973588/
RECORD: Rec_0311904 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
inhibition of fusion in HeLa cells
10 μM
IC50
PaperPubMed PMID: 16973588 PMID16973588 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16973588/
FIRST PREV 1 2 3 NEXT LAST
Showing 5 records on this page · Page 2 of 3