Peptide Database

Peptide NameEsculentin-2-OG2 antimicrobial peptide

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC378H630N98O114S6

DescriptionStandard

        MFTMKKSLLVLFFLGTISLSLCQEERTADEEDNGEVEEVKRGLFTLIKGAAKLIGKTVAKEAGKTGLELMACKITHQC
    

Molecular Weight8564.02 Da

Isoelectric Point (pI)6.56

Net Charge (pH 7.0)-0.42

Net Charge (pH 7.4) -0.76

Charge Density (pH 7.0) -0.0054

GRAVY Index0.07

Hydrophobic Moment 0.64

Boman Index0.07

Instability Index21.57

Aliphatic Index 97.56

Aromaticity 0.0513

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3432.55

LogP -29.96

H-bond Donors 122.0

H-bond Acceptors 121.0

Rotatable Bonds 304.0

Heavy Atoms 596.0

Ring Count 5.0

Amide Bonds 80.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0021571 VERIFIED: NO

Provenance & Taxonomy

OrganismOdorrana grahami [Animal]

FamilyEsculentin

Tax ID167935

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function